Wi-Fi Live-Streaming Centrifuge Force Microscope for Benchtop Single-Molecule Experiments
نویسندگان
چکیده
منابع مشابه
A wireless centrifuge force microscope (CFM) enables multiplexed single-molecule experiments in a commercial centrifuge.
The centrifuge force microscope (CFM) was recently introduced as a platform for massively parallel single-molecule manipulation and analysis. Here we developed a low-cost and self-contained CFM module that works directly within a commercial centrifuge, greatly improving accessibility and ease of use. Our instrument incorporates research grade video microscopy, a power source, a computer, and wi...
متن کاملMultiplexed single-molecule force spectroscopy using a centrifuge.
We present a miniature centrifuge force microscope (CFM) that repurposes a benchtop centrifuge for high-throughput single-molecule experiments with high-resolution particle tracking, a large force range, temperature control and simple push-button operation. Incorporating DNA nanoswitches to enable repeated interrogation by force of single molecular pairs, we demonstrate increased throughput, re...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2020
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2020.10.017